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23andMe Declares Bankruptcy and AI Server Competition Intensifies
March 24, 2025 Newsletter

Markets and Business News
S&P 500 and Nasdaq Snap Four-Week Losing Streaks
On Friday, March 21, the S&P 500 and Nasdaq ended a volatile week on a high note, snapping their four-week losing streaks with a last-minute rally driven by Big Tech gains. The Dow closed flat, but the broader market saw relief after the Federal Reserve’s midweek decision to hold interest rates steady and project two cuts for 2025. Despite earlier struggles in 2025, with both indexes entering correction territory, the late surge was fueled by optimism around tariff hopes and a stabilizing economic outlook, though analysts noted lingering uncertainties like President Trump’s tariff policies could still sway markets.
The rally didn’t fully erase weekly concerns, as companies like FedEx saw a 6.5% stock drop after slashing its 2025 forecast, citing a weaker economic outlook, while steelmaker Nucor slipped 5.8% due to soft pricing pressures. Meanwhile, Carnival Corporation bucked the trend, reporting record first-quarter results and raising its full-year guidance, signaling strength in specific sectors. Market watchers, including 22V Research’s Dennis Debusschere, suggested that post-Fed focus would shift back to tariffs and AI growth trajectories, with some like Capital Economics’ John Higgins warning of an earlier-than-expected AI bubble burst potentially looming in 2025 rather than 2026.
23andMe Files for Bankruptcy
Reuters reported on March 20, 2025, with updates trending through the weekend, that genetic testing firm 23andMe filed for Chapter 11 bankruptcy protection to facilitate a $50 million sale, alongside CEO Anne Wojcicki’s resignation. The company, once a pioneer in consumer DNA testing, faced multiple failed takeover bids and financial strain, with its filing announced on Sunday, March 23. This marked a dramatic fall for a firm valued at billions in its heyday, reflecting broader challenges in the biotech sector.
The bankruptcy news sparked speculation online, with some tying it to market saturation and others to operational missteps. Its timing alongside Wall Street’s rally highlighted a stark contrast between Big Tech’s gains and smaller firms’ struggles. Investors viewed 23andMe’s plight as a cautionary tale of overhyped sectors, with its fate now hinging on a buyer emerging from the Chapter 11 process, while the market awaited broader biotech ripple effects.
AI Server Competition Pressures Margins
New reports have detailed how an “increasingly competitive AI Servers landscape” was squeezing profit margins for tech firms, with JPMorgan analysts pointing to aggressive pricing as a key challenge. One unnamed company, which narrowly avoided delisting in February after late SEC filings, faced scrutiny as its stock fluctuated amid this pressure. The rise of AI demand has spurred innovation but also intensified cost wars, impacting gross margins and raising questions about sustainability in the sector.
This trend tied into broader market narratives, as some speculated it could signal an earlier AI bubble burst, a view echoed by Capital Economics’ John Higgins. While Big Tech buoyed the Nasdaq’s Friday rally, smaller players in the AI ecosystem struggled to maintain profitability, reflecting a market at a crossroads. Investors were left weighing AI’s long-term promise against immediate financial strain, with tariff policies adding another layer of complexity to the tech outlook.
Dollar General Outlines Aggressive 2025 Expansion
Dollar General Corporation announced in its annual 10-K filing on March 21 that it plans to open approximately 575 new stores and remodel or relocate over 4,000 existing locations throughout the year. The retailer, which saw a 2.54% stock bump that Friday, aimed to capitalize on its discount model amid economic uncertainty, positioning itself as a go-to for budget-conscious consumers. The filing highlighted a robust fiscal year ending January 31, 2025, despite a choppy retail environment signaled by Canada’s shrinking sales.
The expansion news stood out against a weekend backdrop where consumer spending fears dominated, as seen in FedEx’s slashed forecast. Dollar General’s strategy leaned on physical growth over digital pivots, contrasting with firms like Meta, which mulled a subscription model for Facebook in the U.K. Investors welcomed the clarity, though some questioned whether the aggressive rollout could strain margins if economic conditions worsen, making it a key storyline to track into mid-2025.

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